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2018….Dukesway Academy will be supporting Sickle Cell Disease


Let us get ready – become more knowledgeable…get ready for fundraisers, donations, and participation in events…..


What is Sickle Cell Disease?


Sickle Cell Disease is an inherited disease that affects our hemoglobin.
Inherited means it is passed from mothers and fathers to their
children. Hemoglobin is a special protein substance inside the red blood cells that is responsible for carrying oxygen from the lungs and takes it to every part of the body.  Every person has two copies of the hemoglobin gene.  A change in the hemoglobin from the normal hemoglobin type may cause the symptoms of Sickle Cell Disease.  Hemoglobin also gives blood its rich red color.

Sickle Cell Disease can be a chronic illness.  Chronic illnesses is an extremely expensive and highly stressful health-care crisis.  Chronic illness is a challenge for many patients and their family members.  Chronic illness is defined as a condition that last over one year, limits the persons activities and requires on-going treatment and health care maintenance.  Sickle Cell Disease has been placed on the back burner and many people are not aware of this condition.  Education, testing and counseling is vitally important for persons affected by a chronic illness.

Sickle Cell Disease is a group of related disorders that affect the red blood cells.  Sickle Cell Disease occurs when a person inherits two sickle cell genes or a combination of one sickle cell gene plus any one of several other abnormal hemoglobin gene that affect the red blood cells.

Most people have normal/adult hemoglobin genes symbolized by the letter “AA”. Normal red blood cells are soft, smooth and round. With Sickle Cell Disease, the red blood cells become hard, sticky, and their shape is like a banana or sickle.  Sickle red blood cells have trouble moving through small blood vessels.  Sometimes they clog up the blood vessels so that blood cannot

bring oxygen to the tissues. This clogging causes severe pain and other problems. Sickle Cell Disease can cause many complications.

The most common problems are:

  • Pain

  • Infections

  • Anemia (low blood)

  • Damage to the body organs.

The most common forms of Sickle Cell Disease are:

  • Sickle Cell Anemia (SS)

  • Sickle Cell Hemoglobin C Disease (SC)

  • Sickle Cell Harlem Disease

Sickle Beta Thalassemia is a less common form of Sickle Cell Disease. The effects of Sickle Cell Disease vary greatly from one person to the next.

It is important for everyone to get tested so they will know their
hemoglobin type and the possibilities of passing sickle genes to their children.

There are several possibilities for children whose parent(s) have Sickle Cell Trait or Sickle Cell Disease.  Genes are passed from parents to their children.

When one parent has Sickle Cell Anemia (SS) and the other parent has normal hemoglobin (AA), all their children will have Sickle Cell Trait (AS).

Health Problems
Related To Sickle Cell


The effects vary greatly
from one person to the
next person.




Organ Damage (heart,
lungs, kidney, brain,
abdomen, spleen, eyes
and liver)


Complications during

Hand and foot

Leg Ulcers


Chest pains and
trouble breathing

Strokes (i.e. heart and


Blood in the urine


Painful erection in men

Exhaustion and tiring

Delayed onsets of
puberty and growth
retardation in both


Frequency of urination

Kidney infections

Destruction of parts of
the bones

Disturbance in vision

Enlargement of spleen
or heart

Heart murmurs

Poor appetite

When one parents have Sickle Cell Trait (AS) and the other parent as Sickle Cell Anemia (SS), the chances for each pregnancy are:

  • 1 in 2 (50%) that the baby will have Sickle Cell Trait (AS)
  • 1 in 2 (50%) that the baby will have Sickle Cell Anemia (SS)
Remember, every person
has two copies of
hemoglobin genes
Parent with Sickle Cell
Anemia (AS)
Parent with Normal
Hemoglobin (SS)

If both parents have Sickle Cell Anemia (SS), all their children will have Sickle Cell Anemia (SS).

Copyright (C) 2005 Sickle Cell Foundation Support Group, Inc.
All Rights Reserved.
E-Mail: info@sicklecellsupportgroup.org



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